研究方向
光是对于植物生长发育最重要的环境信号，本实验室多年来筛选获得了许多参与植物光形态建成的正向和负向调控因子，我们将深入解析这些因子之间的相互作用及其在光信号传导通路中的作用，我们还将寻找参与光信号通路的新因子，并探讨光与植物内源激素协同调控植物发育的机制。非编码RNA是不翻译成蛋白质而直接以RNA形式行使生物学功能的RNA分子，我们将探索中等长度非编码RNA参与和调控高等植物生长发育及环境信号响应的作用机理。杂种优势是杂交子一代在多个性状上优于其亲本的生物学现象，我们将以水稻和拟南芥为研究对象，在分子和细胞水平上解析杂种优势形成的遗传机理。我们还通过大数据的生物信息学分析和数学建模，开展水稻分子设计育种新技术的研究。
代表性科研论文
1. Lin, F., Jiang, Y., Li, J., Yan, T., Fan, L., Liang, J., Chen, Z. J., Xu, D. and Deng, X.W. (2018). B-BOX DOMAIN PROTEIN28 Negatively Regulates Photomorphogenesis by Repressing the Activity of Transcription Factor HY5 and Undergoes COP1-Mediated Degradation. Plant Cell 30, 2006-2019.
2. Ling, J.J., Li, J., Zhu, D., and Deng, X.W. (2017). Noncanonical role of Arabidopsis COP1/SPA complex in repressingBIN2-mediated PIF3 phosphorylation and degradation in darkness. Proc Natl Acad Sci U S A 114, 3539-3544.
3. Li, K., Yu, R., Fan, L.M., Wei, N., Chen, H., and Deng, X.W. (2016). DELLA-mediated PIF degradation contributes to coordinationof light and gibberellin signalling in Arabidopsis. Nature communications 7, 11868.
4. Yang, L., Li, B., Zheng, X.Y., Li, J., Yang, M., Dong, X., He, G., An, C., and Deng, X.W. (2015). Salicylic acid biosynthesis is enhancedand contributes to increased biotrophic pathogen resistance in Arabidopsis hybrids. Nature communications 6, 7309.
5. Wang, Y., Fan, X., Lin, F., He, G., Terzaghi, W., Zhu, D., and Deng, X.W. (2014). Arabidopsis noncoding RNA mediates control ofphotomorphogenesis by red light. Proc Natl Acad Sci U S A 111, 10359-10364.
6. Feng, S., Martinez C., Gusmaroli G., Wang Y., Zhou J., Wang F., Chen L., Yu L., Iglesias-Pedraz J. M., Kircher S., Schafer E., Fu X.,Fan L. M. and Deng X. W. (2008). Coordinated regulation of Arabidopsis thaliana development by light and gibberellins. Nature 451, 475-479.
7. Wang, H., Ma, L.G., Li, J.M., Zhao, H.Y., and Deng, X.W. (2001). Direct interaction of Arabidopsis cryptochromes with COP1 in lightcontrol development. Science 294, 154-158.
8. Deng, X.W., Matsui, M., Wei, N., W agner, D., Chu, A.M., Feldmann, K.A., and Quail, P.H. (1992). C OP1, an Arabidopsis regulatorygene, encodes a protein with both a zinc-binding motif and a G bet a homologous domain. Cell 71, 791-801.
