YUXIN YIN

Main Publication:

1. Yin, Y., Tainsky, M. A. Bischoff, F. A., Strong, L.C. and Wahl, G. M. (1992). Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70:937-948.
2. Yin, Y., Terauchi, Y., Solomon, G. G., Aizawa, S., Rangarajan, P. N., Yazaki, Y., Kadowaki, T, and Barrett, J. C. (1998). Involvement of p85 in p53-dependent apoptotic response to oxidative stress. Nature 391: 707-710.
3. Yin, Y.*, Liu, Y. X., Jin, Y. J., Hall, E. J., and Barrett, J. C. (2003). PAC1 phosphatase is a transcription target of p53 in signaling apoptosis and growth suppression. Nature 422:527-531.
4. Shen, W. H., Balajee, A. B., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., and Yin, Y.* (2007). Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell,128: 157-170.
5. Sun, Z., Huang, C., Gu, T., Shen, W.H., and Yin, Y.*. (2014). PTEN C-terminal Deletion Causes Genomic Instability and Tumor Development. Cell Rep. 6, 1-12.
6. Liang, H., He, S., Yang, J., Jia, X., Wang, P., Chen, X., Zhang, Z., Zou, X., McNutt, M.A., Shen, W.H.,* and Yin, Y.*. (2014). PTENα is a PTEN isoform Translated through Alternative Initiation and Regulates Mitochondrial Function. Cell Metab. 19, 836-848.
7. Chen, Z., Zhu, M., Yang, J., Liang, H., He, J., He, S., Wang, P., Kang, X., McNutt, M.A., Yin, Y.*, and Shen, W.H.* (2014). PTEN Interacts with Histone H1 and Controls Chromatin Condensation. Cell Rep. 8, 2003-2014.
8. Wang, G., Li, Y., Wang, P., Liang, H., Cui, M., Zhu, M., Guo, L., Su, Q., Sun, Y., McNutt, M.A., and Yin, Y.*. (2015). PTEN regulates RPA1 and protects DNA replication forks. Cell Res. 25, 1189-1204.
9. Lu, D., Liu, L., Ji, X., Gao, Y., Chen, X., Liu, Y., Liu, Y., Zhao, X., Li, Y., Li, Y., Jin, Y., Zhang, Y., McNutt, M.A., and Yin, Y.*(2015).The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation. Nat Immunol., 16, 1263-1273.
10. Feng, J., Liang, J., Li, J., Li, Y., Liang, H., Zhao, X., McNutt, M.A., and Yin, Y.* (2015). PTEN Controls the DNA Replication Process through MCM2 in Response to Replicative Stress. Cell Reports, 13, 1295-1303.
* Corresponding author