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LUHUA LAI -
LUHUA LAI
- Emaillhlai(AT)pku.edu.cn
- Phone010-62757520
- DepartmentCollege of Chemistry and Molecular Engineering, Peking University
- Research Interest
- Homepagehttp://mdl.ipc.pku.edu.cn
Main Publications:1. Liang, H. H.; Chen, H.; Fan, K. Q.; Wei, P.; Guo, X. R.; Jin, C. W.; Zeng, C.; Tang, C.; Lai, L. H.*, De Novo Design of a beta alpha beta Motif. Angew. Chem. Int. Ed. 2009, 48, (1
Main Publications:
1. Liang, H. H.; Chen, H.; Fan, K. Q.; Wei, P.; Guo, X. R.; Jin, C. W.; Zeng, C.; Tang, C.; Lai, L. H.*, De Novo Design of a beta alpha beta Motif. Angew. Chem. Int. Ed. 2009, 48, (18), 3301-3303.
2. Yang, K., Bai, H. J., Ouyang，Q., Lai, L. H.*, Tang, C., Finding multiple target optimal intervention in disease-related molecular network. Mol. Syst. Biol. 2008, 4:228.
3. Wei，D. G.§, Jiang, X. L.§, Zhou, L., Chen, J., He, C., Yang, K., Liu, Y., Pei, J. F., Lai, L. H.*,. Identifying multi-target inhibitors by combining molecular docking with common pharmacophore matching. J. Med. Chem. 2008, 51 (12), 3360 - 3366.
4. Liu S§, Liu SY§, Zhu XL, Liang HH, Cao AN, Chang ZJ and Lai LH*. Nonnatural protein-protein interaction-pair design by key residues grafting. Proc Natl Acad Sci USA 2007, 104:5330-5335.
5. Yang K, Ma WZ, Liang HH, Ouyang Q, Tang C and Lai LH*. Dynamic simulations on the Arachidonic Acid Metabolic Network. PLoS Compt. Biol., 2007, 3:523-530.
6. Zhang, Z. Q.; Chen, H.; Lai, L. H.*, Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential. Bioinformatics 2007, 23, (17), 2218-2225.
7. Chen, H.; Wei, P.; Huang, C. K.; Tan, L.; Liu, Y.; Lai, L. H.*, Only one protomer is active in the dimer of SARS 3C-like proteinase. J. Biol. Chem. 2006, 281, (20), 13894-13898.
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