研究方向：神经化学生物学

发展化学探针技术，为神经科学的研究提供新工具、新方法，实现针对神经系统实时、定量、高时空分辨的观测。具体研究方向包括：发展可遗传编码的膜电位荧光探针及相应的光学成像技术，研究神经细胞网络的电生理活性；发展蛋白质、核酸化学标记技术，研究与神经活性相关的生物大分子相互作用；研究与学习、记忆相关的蛋白质时空动态调控机制。

代表性科研论文：

1. Liu, S.^#, Lin, C.^#, Xu, Y.^#, Luo, H., Peng, L., Zeng, X., Zheng, H., Chen, P. R.* andZou, P.* (2021). A far-red hybrid voltage indicator enabled by bioorthogonal engineering of rhodopsin on live neurons.Nat. Chem. 13, 472-479.

2. Wang, P.^#, Tang, W.^#, Li, Z.^#, Zou, Z., Zhou, Y., Li, R., Xiong, T., Wang, J.* andZou, P.*(2019). Mapping spatial transcriptome with light-activated proximity-dependent RNA labeling.Nat. Chem. Biol. 15, 1110-1119.

3. Zhou, Y.^#, Wang, G.^#, Wang, P., Li, Z., Yue, T., Wang, J. andZou, P.* (2019). Expanding APEX2 substrates for proximity-dependent labeling of nucleic acids and proteins in living cells.Angew. Chem. Int. Ed. Engl. 58, 11763-11767.

4. Xu, Y.^#, Peng, L.^#, Wang, S.^#, Wang, A.^#, Ma, R., Zhou, Y., Yang, J., Sun, D. E., Lin, W., Chen, X. andZou, P.* (2018). Hybrid indicators for fast and sensitive voltage imaging.Angew. Chem. Int. Ed. Engl. 57, 3949-3953.

5. Ding, T.^#, Zhu, L.^#, Fang, Y., Liu, Y., Tang, W. andZou, P.* (2020). Chromophore-assisted proximity labeling of DNA reveals chromosomal organization in living cells.Angew. Chem. Int. Ed. Engl. 59, 22933-22937.